McSweeney N(1), Brew S, Bhate S, Cox T, Roebuck DJ, Ganesan V. Author information: (1)The Wolfson Centre, Mecklenburgh Square, London, UK. October 16th 2017. A Vein of Galen Malformation (VOGM) is a type of cerebral arteriovenous malformation (AVM), which is a rare blood vessel abnormality inside the brain. In VOGMs, misshapen arteries in the brain connect directly with veins, instead of connecting with capillaries, which help slow blood flow. PURPOSE: We performed a systematic review of the literature to determine outcomes and predictors of good outcomes following endovascular treatment of vein of Galen malformations. Article: Vein of Galen Malformation: Outcome after Embolization. World Federation of Interventional & Therpeutic Neuroradiology Congress: Budapest, Hungary. Embryology Vein of Galen malformations arise as a result of direct arteriovenous communications between the arterial network and the median prosencephalic vein. This usually grossly dilated vein was recognised by Raybaud and colleagues to be the embryonic precursor of the vein of Galen—the median vein of the prosencephalon. OBJECTIVE: To describe our experience of treating children with vein of Galen aneurysmal malformation (VGM) in a single UK centre between 2003 and 2008. This was a retrospective observational study on a consecutive cohort of patients with VGAM. The authors report severe intracranial AVMs, including vein of Galen aneurysmal malformation, which was symptomatic at birth or during infancy, … However, most fetal series are too small to allow reliable statistical assessment of potential prognostic indicators. This causes a rush of high-pressure blood into the veins. To describe the long‐term outcomes of children by the time they reached school age with vein of Galen aneurysmal malformation (VGAM). 6 This malformation develops before the formation of the vein of Galen and straight sinus, and the pouch drains via a falcine sinus to the superior sagittal sinus. DATA SOURCES: We used Ovid MEDLINE, Ovid Embase, and the Web of Science. Management and outcome of vein of Galen malformation. 3. Method. Vein of Galen malformation has been associated with capillary malformation-arteriovenous malformation (CM-AVM), which is a newly recognized autosomal dominant disorder, caused by mutations in the RASA1 gene in 6 families. To study the clinical outcomes of treating vein of Galen aneurysmal malformations (VGAM), we assessed our patient cohort using standardized cognitive and functional measures. Vein of Galen aneurysmal malformation (VGAM) is an intracranial arteriovenous malformation of the choroidal system that develops in the embry-onic period.1 The malformation creates a persistent alternative embryonic deep venous drainage pathway, which can impact on the perfusion of the developing brain and the cardiac and cere-bral haemodynamics. Vein of Galen aneurysmal malformations (VGAMs), probably better termed as median prosencephalic arteriovenous fistulas, are uncommon intracranial anomalies that tend to present dramatically during early childhood with features of a left-to-right shunt and high-output cardiac failure. The successful treatment of vein of Galen malformations remains a complex therapeutic challenge. Vein of Galen aneurysmal malformation (VGAM) is a rare fetal anomaly, the neurological outcome of which can be good with appropriate perinatal management. Abstract The neurodevelopmental outcome after endovascular treatment of vein of Galen malformation (VOGM) in 27 patients seen between 1983 and 2002 was assessed by chart review and parental questionnaires at the University of California, San Francisco. The authors’ analysis of clinical history and research literature suggests that vein of Galen malformations treated with endovascular embolization can result in an acceptable mortality rate, complications, and good clinical outcome. Rennie et al., Course and outcome of post-neonatal presentations of vein of Galen malformation & Outcomes in neonatal vein of Galen malformation. BACKGROUND: Outcomes after endovascular embolization of vein of Galen malformations remain relatively poorly described. 2. Instead of connecting with capillaries, which help slow blood flow to allow reliable assessment. Patients with VGAM school age with vein of Galen malformations remains a complex therapeutic challenge in neonatal vein of malformation. 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